Hi Piang,
You can write a tmsh script to create the iFile file and config object. The steps in the link I gave are fairly complete (https://devcentral.f5.com/Community/GroupDetails/tabid/1082223/asg/53/aft/2159165/showtab/groupforums/Default.aspx2235504).
That said, I would questions why you want to use LTM to host hundreds of files. Each file is loaded into TMM memory and takes away from what is available for load balancing and the other main responsibilities you use an ADC for. Wouldn't it be cheaper to set up a remotely hosted static web application for this?
Aaron