Sorry, but I'll try to answer only your first question right now. We'll come back to others once we have time, or maybe others can help.
"Questions: 1. Client from net goes to VS1 (SNAT off) is redirected to SRV (source address is seen, destination nat is in place to pass traffic to SRV). I assume that return traffic from SRV is hitting VS 0/0 (am I right?) VS 0/0 have snat off. And I also assume that source address of SRV is changed to VS1 IP (am I also right?). If not, should I do some SNAT on VS 0/0?"
- If VS1 is from where client comes in (another VS with a pool attached), then the return traffic won't go past the VS 0/0, but it will be routed back from the same VS1. Client will see the source IP address of return packets, the same as VS1 external listener IP. Traffic will go through the VS0/0, only if the session was initiated by SRV. (E.g SRV making a DNS request to 8.8.8.8 will be routed via VS0/0, and no NAT will be applied in F5).