BD Key Failed and F5 stucked Offline state after update

The botd service is dependent on the database, it might be that the database can't start for some reason.

To begin troubleshooting this issue, review the log data (/var/log/ltm and other files in that directory) and use the "bigstart status" command to see precisely what services can't start.

Alternatively, Support can assist with it:

https://my.f5.com/manage/s/article/K2633